Access Millions of Variant Genes through Metagenomics

Thousands of natural product pathways with complete operons and millions of novel genes from the most diverse microbial environment on earth


Soil Metagenomics Using BIGDNA™ Technology

Our research scientists harness the naturally occurring variety of microbial life present in soil and other environments to develop improved enzymes, cultures and drugs. The science of metagenomics, tapping into natural biodiversity using genetic methods, has led to unprecedented discoveries about microbiomes associated with humans and other habitats. Varigen Biosciences uses and improves upon this wealth of biodiversity using proprietary methods to create novel variants that have beneficial applications for medical, agricultural and industrial use.

Product Lines

Varigen Biosciences is developing revolutionary products for the sequence specific capture, amplification, sequencing, and over expression of long DNA (20-150 Kb) to dramatically simplify the production of natural products.

BIGDNA™ Soil Metagenomic Libraries are the only large insert (>100 kb) libraries that contain full pathways and have been sequenced. Please see products page for more details.

Our History

Varigen was founded in 2016. Our research team has over 125 years of expertise in molecular biology and microbiology.

CALL: 608.444.9518

Varigen Biosciences
505 S. Rosa Road
Suite 15
Madison, WI 53719


Varigen™ Biosciences, Natural Products by Design™  is an NIH- and NSF-funded effort to harness naturally occurring microbial diversity to develop the next generation of natural products through genomics and metagenomics. Varigen's team is led by researchers with over 125 years of combined experience.